Our main interest is synthetic organic chemistry. Research in our laboratory focuses on four major areas. These are (1) new synthetic methodology, (2), asymmetric synthesis (3) natural product synthesis, and (4) new materials. The development of new methods for the preparation of enantiomerically pure compounds is an area of intense scrutiny. In this context, the design and execution of transformations which utilize catalytic amounts of chiral Lewis acids to install chirality in prochiral substrates has become very important. A program of high priority in our group is the development of synthetically useful radical reactions, especially, enantioselective variants using chiral Lewis acid catalysis. The stereoselectivity in these reactions will be established by manipulating the geometry of the reactive complex by judicious choice of simple, readily available, and easily removable achiral templates, ligands, and Lewis acids. We have recently demonstrated that high enantioselectivity can be achieved in conjugate addition of carbon radicals, amines, and carbanions to α,β-unsaturated carboxyl derivatives using catalytic amounts chiral Lewis acids. A better understanding of these reactions, their refinement, and extension to other bond forming processes are projects under investigation.

We are located on the North Dakota State University campus in Fargo, ND. Our labs are housed in Dunbar Hall, at the heart of campus. Feel free to look around and get to know a little about us and our chemistry.

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  • Hari recieved the ND EPSCoR doctoral dissertation fellowship. Congrats Hari!,
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